BDBM383125 (1R,2S)-4-(9b-((3-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)-2-methylcyclohexane-1-carboxylic acid (2 Single Diastereomers)::US10273259, Example 836::US10273259, Example 837::US10711020, Example 837

SMILES C[C@H]1CC(CC[C@H]1C(O)=O)C(=O)N1CCC2(C1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccc(F)c1

InChI Key InChIKey=VSNITFSVOGKQJM-PEZFPZIYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 383125   

TargetNuclear receptor ROR-gamma(Mus musculus)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM383125((1R,2S)-4-(9b-((3-fluorophenyl)sulfonyl)-7-(perflu...)
Affinity DataIC50:  13nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM383125((1R,2S)-4-(9b-((3-fluorophenyl)sulfonyl)-7-(perflu...)
Affinity DataIC50:  56nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM383125((1R,2S)-4-(9b-((3-fluorophenyl)sulfonyl)-7-(perflu...)
Affinity DataIC50:  13nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Mus musculus)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM383125((1R,2S)-4-(9b-((3-fluorophenyl)sulfonyl)-7-(perflu...)
Affinity DataIC50:  56nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent