BDBM383229 4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacenaphthylen-7-yl)-N- (1-methyl-1H-pyrazol-5- yl)pyrimidin-2-amine::US10278975, Compound I-15 R::US11376260, Example I-15S
SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OC[C@H](Cc3ccccc3)c3nnc(c1)n23
InChI Key InChIKey=UMMWPQCPEZFOCL-KRWDZBQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 383229
Affinity DataIC50: 2.24nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair