BDBM383619 (1-cyclobutylpiperidin-3-yl)(6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)methanoe::US10280149, Example 132

SMILES O=C(C1CCCN(C1)C1CCC1)c1ccc2CCCCCc2c1

InChI Key InChIKey=MYYHWQJQNCTUIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383619   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383619((1-cyclobutylpiperidin-3-yl)(6,7,8,9-tetrahydro-5H...)
Affinity DataIC50:  55.3nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent