BDBM385118 US10287267, Compound 274::US10508099, Compound 274::US10556885, Compound 274::US11174244, Compound 274::US11673881, Compound 274
SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)CN3CC[C@@H](F)C3)cc2c1
InChI Key InChIKey=AHVVQOPDAHKCJF-QGZVFWFLSA-N
Data 12 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 385118
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics
US Patent
Biosplice Therapeutics
US Patent
Affinity DataEC50: 5.90nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:The GSK3B kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies-a Divisio...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics
US Patent
Biosplice Therapeutics
US Patent
Affinity DataEC50: 5.90nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...More data for this Ligand-Target Pair