BDBM385254 US10287267, Compound 791::US10508099, Compound 791::US10556885, Compound 791::US11174244, Compound 791::US11673881, Compound 791
SMILES Cn1ncc(c1CN1CCCCC1)-c1ccc2cnc(NC(=O)C3CC4(C3)CN(CCF)C4)cc2c1
InChI Key InChIKey=KWMNKBFIVSGOCP-UHFFFAOYSA-N
Data 12 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 385254
Affinity DataEC50: 5nMAssay Description:The GSK3B kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies-a Divisio...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics
US Patent
Biosplice Therapeutics
US Patent
Affinity DataEC50: 2.20nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics
US Patent
Biosplice Therapeutics
US Patent
Affinity DataEC50: 2.20nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair