BDBM385996 US10287300, Compound A4::{2-(4-Chlorophenyl)-2-[4-(7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-yl)-piperazin-1-yl]-ethyl}-dimethylamine

SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCCOc12)c1ccc(Cl)cc1

InChI Key InChIKey=CEGFMYOPNFFWHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385996   

TargetProline-rich AKT1 substrate 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM385996(US10287300, Compound A4 | {2-(4-Chlorophenyl)-2-[4...)
Affinity DataIC50:  300nMAssay Description:A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM385996(US10287300, Compound A4 | {2-(4-Chlorophenyl)-2-[4...)
Affinity DataIC50: >1.00E+3nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent