BDBM387101 2-(cis-6-(2-(2H-1,2,3-triazol-2- yl)benzoyl)ocathydro-1H-pyrrolo[2,3- c]pyridin-1-yl)-3-methylisonicotinonitrile::US9938276, A15

SMILES Clc1cc(C#N)c(cn1)N1CC[C@@H]2CCN(C[C@H]12)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=RIYBMHQMNVHTTD-YWZLYKJASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387101   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387101(2-(cis-6-(2-(2H-1,2,3-triazol-2- yl)benzoyl)ocathy...)
Affinity DataIC50:  1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387101(2-(cis-6-(2-(2H-1,2,3-triazol-2- yl)benzoyl)ocathy...)
Affinity DataIC50:  84.8nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent