BDBM387108 (3aR, 7aR)-(2-(2H-1,2,3-triazol-2- yl)phenyl)(1-(4-methoxypyridin-2- yl)hexahydro-1H-pyrrolo[2,3-c]pyridin- 6(2H)-yl)methanone::US9938276, B3

SMILES CCc1ccnc(c1)N1CC[C@@H]2CCN(C[C@H]12)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=XHAWEXDHHAWEDC-RXVVDRJESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387108   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387108((3aR, 7aR)-(2-(2H-1,2,3-triazol-2- yl)phenyl)(1-(4...)
Affinity DataIC50:  1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387108((3aR, 7aR)-(2-(2H-1,2,3-triazol-2- yl)phenyl)(1-(4...)
Affinity DataIC50:  1.01E+3nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent