BDBM387121 ((3aR, 7aR)-1-(1,7-naphthyridin-8- yl)hexahydro-1H-pyrrolo[2,3-c]pyridin- 6(2H)-yl)(2-(2H-1,2,3-triazol-2- yl)phenyl)methanone::US9938276, B16

SMILES O=C(N1CC[C@H]2CCN([C@H]2C1)C1=NC=CC2C=CC=CC12)c1ccccc1-n1nccn1

InChI Key InChIKey=UYFZCHQKRVRDBA-XKXWHVAQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387121   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387121(((3aR, 7aR)-1-(1,7-naphthyridin-8- yl)hexahydro-1H...)
Affinity DataIC50:  1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387121(((3aR, 7aR)-1-(1,7-naphthyridin-8- yl)hexahydro-1H...)
Affinity DataIC50:  750nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent