BDBM387137 2-((3aS, 7aS)-6-(2- (trifluoromethoxy)benzoyl)octahydro- 1H-pyrrolo[2,3-c]pyridin-1- yl)isonicotinonitrile::US9938276, D3

SMILES FC(F)(F)Oc1ccccc1C(=O)N1CC[C@H]2CCN([C@H]2C1)c1cc(ccn1)C#N

InChI Key InChIKey=UBUBYMKJOUFTPK-RDJZCZTQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387137   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387137(2-((3aS, 7aS)-6-(2- (trifluoromethoxy)benzoyl)octa...)
Affinity DataIC50:  1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387137(2-((3aS, 7aS)-6-(2- (trifluoromethoxy)benzoyl)octa...)
Affinity DataIC50:  79.1nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent