BDBM387144 2-((3aR, 7aR)-6-(4-fluoro-2(2H-1,2,3- triazol-2-yl)benzoyl)octahydro-1H- pyrrolo[2,3-c]pyridin-1- yl)isonicotinonitrile::US9938276, E4

SMILES Fc1ccc(c(c1)C(=O)N1CC[C@H]2CCN([C@H]2C1)c1cc(ccn1)C#N)-n1nccn1

InChI Key InChIKey=WKIBIIXLXWJDQE-JXFKEZNVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387144   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387144(2-((3aR, 7aR)-6-(4-fluoro-2(2H-1,2,3- triazol-2-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387144(2-((3aR, 7aR)-6-(4-fluoro-2(2H-1,2,3- triazol-2-yl...)
Affinity DataIC50:  62.7nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent