BDBM387153 2-{(3aR, 7aR)-6-[(2-cyclopropyl-6- methoxypyridin-3-yl)carbonyl]octahydro- 1H-pyrrolo[2,3-c]pyridin-1-yl}pyridine-4- carbonitrile::US9938276, E13

SMILES COc1ccc(C(=O)N2CC[C@H]3CCN([C@H]3C2)c2cc(ccn2)C#N)c(n1)C1CC1

InChI Key InChIKey=KDBJXYVBIKLNCL-LPHOPBHVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387153   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387153(2-{(3aR, 7aR)-6-[(2-cyclopropyl-6- methoxypyridin-...)
Affinity DataIC50:  1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387153(2-{(3aR, 7aR)-6-[(2-cyclopropyl-6- methoxypyridin-...)
Affinity DataIC50:  980nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent