BDBM387345 2-cyclopropyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}pyrrolo[2,1-f][1,2,4]triazin-2-yl)pyridine::US10292985, Example 27

SMILES C1CC1c1cccc(n1)-c1nc(-n2ccc3cnccc23)c2cccn2n1

InChI Key InChIKey=DLYGJFNPZNOGRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387345   

TargetTGF-beta receptor type-2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM387345(2-cyclopropyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}...)
Affinity DataIC50: >1.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM387345(2-cyclopropyl-6-(4-{1H-pyrrolo[3,2-c]pyridin-1-yl}...)
Affinity DataIC50:  1.30nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent