BDBM387795 Cis-N-(3-Fluoropiperidin-4-yl)-1-(2-fluoropyridin-4-ylmethyl)-4,7-difluoro-1H-indole-3-carboxamide hydrochloride (Isomer-I)::US10294217, Example 22::US10294217, Example 23::US10294217, Example 24::US10294217, Example 25

SMILES FC1CNCCC1NC(=O)c1cn(Cc2ccnc(F)c2)c2c(F)ccc(F)c12

InChI Key InChIKey=WLZWNYJYLDDHQB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 387795   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

US Patent
LigandPNGBDBM387795(Cis-N-(3-Fluoropiperidin-4-yl)-1-(2-fluoropyridin-...)
Affinity DataEC50:  1.50E+3nMAssay Description:A stable CHO cell line expressing recombinant human Muscarinic M1 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

US Patent
LigandPNGBDBM387795(Cis-N-(3-Fluoropiperidin-4-yl)-1-(2-fluoropyridin-...)
Affinity DataEC50:  1.44E+3nMAssay Description:A stable CHO cell line expressing recombinant human Muscarinic M1 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

US Patent
LigandPNGBDBM387795(Cis-N-(3-Fluoropiperidin-4-yl)-1-(2-fluoropyridin-...)
Affinity DataEC50:  1.39E+3nMAssay Description:A stable CHO cell line expressing recombinant human Muscarinic M1 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

US Patent
LigandPNGBDBM387795(Cis-N-(3-Fluoropiperidin-4-yl)-1-(2-fluoropyridin-...)
Affinity DataEC50:  1.07E+3nMAssay Description:A stable CHO cell line expressing recombinant human Muscarinic M1 receptor and pCRE-Luc reporter system was used for cell-based assay. The assay offe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent