BDBM388198 1-(4-((3,3-difluorocyclopentyl)amino)-5-(4-(3-hydroxy-3-methylbutyl)-1H-1,2,3-triazol-1-yl)pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile::US10294229, Example 347

SMILES CC(C)(O)CCc1cn(nn1)-c1cnc(cc1NC1CCC(F)(F)C1)-n1ncc2cc(cnc12)C#N

InChI Key InChIKey=ZXJRCPSBIZZWNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388198   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM388198(1-(4-((3,3-difluorocyclopentyl)amino)-5-(4-(3-hydr...)
Affinity DataIC50:  2nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent