BDBM388411 US10294246, Compound No. 108

SMILES COc1ccc(CC(=O)N[C@@H](Cc2cc3ccccc3o2)B(O)O)cc1

InChI Key InChIKey=RDVNRGVNNJKUCF-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388411   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM388411(US10294246, Compound No. 108)
Affinity DataIC50:  2.75E+3nMAssay Description:Measurement of Beta5 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human constitutive proteasome (1.25 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM388411(US10294246, Compound No. 108)
Affinity DataIC50: <50nMAssay Description:Measurement of LMP7 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human immunoproteasome (0.25 nM) and se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent