BDBM389316 US9951027, 2-91-2
SMILES CCc1ccc(Nc2nc3cc(ccc3n2[C@@H]2C[C@@H](C)CC(C)(C)C2)C(=O)N(C)C)cc1
InChI Key InChIKey=UUVRQFXUFLOILN-XMSQKQJNSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 389316
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 30nMAssay Description:mIDH1 catalyzes the NADPH-dependent reduction of alpha-ketoglutarate (α-KG) to (2R)-2-hydroxyglutarate (2-HG). NADPH consumption was measured by...More data for this Ligand-Target Pair