BDBM390086 US10323037, Example 98::US9951077, 98

SMILES CO[C@H]1CN(C[C@@H]1n1cc(-c2ccc(Oc3ccccc3F)cc2)c2c(N)n[nH]c(=O)c12)C(=O)C#CC

InChI Key InChIKey=UMTWCRXHTISWGV-UNMCSNQZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390086   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390086(US10323037, Example 98 | US9951077, 98)
Affinity DataIC50:  505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM390086(US10323037, Example 98 | US9951077, 98)
Affinity DataIC50:  505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent