BDBM392369 N-(2-phenyl-1H-pyrrolo[2,3-b] pyridin-5-yl)-2H-triazole-4- carboxamide::US10301280, Compound P-2015

SMILES O=C(Nc1cnc2[nH]c(cc2c1)-c1ccccc1)c1cn[nH]n1

InChI Key InChIKey=LRSCZRCWOMNIRU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392369   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392369(N-(2-phenyl-1H-pyrrolo[2,3-b] pyridin-5-yl)-2H-tri...)
Affinity DataKi:  5.50E+3nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392369(N-(2-phenyl-1H-pyrrolo[2,3-b] pyridin-5-yl)-2H-tri...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent