BDBM392401 N-[2-[3- (ethylsulfamoyl)anilino]pyrimidin-5- yl]-3,4-dimethyl-1H-pyrazole-5- carboxamide::US10301280, Compound P-2050

SMILES CCNS(=O)(=O)c1cccc(Nc2ncc(NC(=O)c3[nH]nc(C)c3C)cn2)c1

InChI Key InChIKey=MKGAGOCVKXZIHW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392401   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392401(N-[2-[3- (ethylsulfamoyl)anilino]pyrimidin-5- yl]-...)
Affinity DataKi: <1.00E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392401(N-[2-[3- (ethylsulfamoyl)anilino]pyrimidin-5- yl]-...)
Affinity DataKi:  5.50E+3nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent