BDBM392438 N-[2-[3-[4- (cyclopropanecarbonyl)piperazin-1- yl]phenyl]-1H-pyrrolo[2,3-b]pyridin- 5-yl]-3,4-dimethyl-1H-pyrazole-5- carboxamide::US10301280, Compound P-2118
SMILES Cc1n[nH]c(C(=O)Nc2cnc3[nH]c(cc3c2)-c2cccc(c2)N2CCN(CC2)C(=O)C2CC2)c1C
InChI Key InChIKey=PDXDRNLUAPVVHW-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 392438
Affinity DataKi: <1.00E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+5nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair