BDBM392438 N-[2-[3-[4- (cyclopropanecarbonyl)piperazin-1- yl]phenyl]-1H-pyrrolo[2,3-b]pyridin- 5-yl]-3,4-dimethyl-1H-pyrazole-5- carboxamide::US10301280, Compound P-2118

SMILES Cc1n[nH]c(C(=O)Nc2cnc3[nH]c(cc3c2)-c2cccc(c2)N2CCN(CC2)C(=O)C2CC2)c1C

InChI Key InChIKey=PDXDRNLUAPVVHW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392438   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392438(N-[2-[3-[4- (cyclopropanecarbonyl)piperazin-1- yl]...)
Affinity DataKi: <1.00E+3nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM392438(N-[2-[3-[4- (cyclopropanecarbonyl)piperazin-1- yl]...)
Affinity DataKi:  1.05E+5nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent