BDBM392563 N-((1-aminoisoquinolin-6-yl)methyl)- 1-((3-chloroquinolin-6-yl)methyl)-3- cyano-1H-pyrazole-4-carboxamide::US10301284, Example 49::US10781200, Example 49

SMILES Nc1nccc2cc(CNC(=O)c3cn(Cc4ccc5ncc(Cl)cc5c4)nc3C#N)ccc12

InChI Key InChIKey=LNXYHPIIXNZTBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392563   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392563(N-((1-aminoisoquinolin-6-yl)methyl)- 1-((3-chloroq...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392563(N-((1-aminoisoquinolin-6-yl)methyl)- 1-((3-chloroq...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent