BDBM392663 US10301286, Example 89

SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1c(C)cc(C)cc1C)C(O)=O

InChI Key InChIKey=ADUOPKMZFRVUSL-NNNZQYNTSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 392663   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM392663(US10301286, Example 89)
Affinity DataEC50:  3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Rattus norvegicus)
Astellas Pharma

US Patent
LigandPNGBDBM392663(US10301286, Example 89)
Affinity DataEC50:  3.10nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 3(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM392663(US10301286, Example 89)
Affinity DataEC50:  780nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM392663(US10301286, Example 89)
Affinity DataEC50:  1.30E+3nMAssay Description:Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent