BDBM393345 3-Fluoro-4-(((1R,3R)-3-isothiocyanatocyclobutoxy)methyl)-3'-(trifluoromethyl)-1,1'-biphenyl::US9963444, Example 47

SMILES Fc1cc(ccc1COC1C[C@@H](C1)N=C=S)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=KGODHBBOHBOYGT-XPIKVJKASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393345   

TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University

US Patent
LigandPNGBDBM393345(3-Fluoro-4-(((1R,3R)-3-isothiocyanatocyclobutoxy)m...)
Affinity DataIC50:  55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent