BDBM393428 N-[5-[(2R,5S,6R)-5-amino-6- fluoro-oxepan-2-yl]-1- cyclopropyl-pyrazol-4-yl]-6- (2,6-difluorophenyl)-5-fluoro- pyridine-2-carboxamide::US9963446, Example 114

SMILES N[C@H]1CC[C@@H](OC[C@@H]1F)c1c(NC(=O)c2ccc(F)c(n2)-c2c(F)cccc2F)cnn1C1CC1

InChI Key InChIKey=GIVOQPYFGTUDRN-ABSDTBQOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393428   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM393428(N-[5-[(2R,5S,6R)-5-amino-6- fluoro-oxepan-2-yl]-1-...)
Affinity DataKi:  0.173nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent