BDBM395241 (5R,7S or 5S,7R)-2-(2-Aminopyridin-4-yl)-6,6-dimethyl-3-(phenylamino)-1,5,6,7-tetrahydro-4H-5,7-methanoindol-4-one::US10308629, Example 3::US10308629, Example 4
SMILES CC1(C)[C@H]2C[C@@H]1C(=O)c1c(Nc3ccccc3)c([nH]c21)-c1ccnc(N)c1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 395241
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 2.93E+3nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 648nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair