BDBM395246 1-4-[rel-(5R,7S)-6,6-Dimethyl-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-5,7-methanoindol-2-yl]pyridin-2-yl-3-ethylurea::US10308629, Example 8
SMILES CCNC(=O)Nc1cc(ccn1)-c1[nH]c2[C@H]3C[C@@H](C(=O)c2c1Nc1ccccc1)C3(C)C
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 395246
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 375nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair