BDBM395248 US10308629, Example 10::rel-(5R,7S)-2-(3-Fluoropyridin-4-yl)-6,6-dimethyl-3-(phenylamino)-1,5,6,7-tetrahydro-4H-5,7-methanoindol-4-one

SMILES CC1(C)[C@H]2C[C@@H]1C(NCc1ccncc1F)=C(C(=S)Nc1ccccc1)C2=O

InChI Key InChIKey=YHNXJITWZKVFPP-CVEARBPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395248   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395248(US10308629, Example 10 | rel-(5R,7S)-2-(3-Fluoropy...)
Affinity DataIC50:  35nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent