BDBM395248 US10308629, Example 10::rel-(5R,7S)-2-(3-Fluoropyridin-4-yl)-6,6-dimethyl-3-(phenylamino)-1,5,6,7-tetrahydro-4H-5,7-methanoindol-4-one
SMILES CC1(C)[C@H]2C[C@@H]1C(NCc1ccncc1F)=C(C(=S)Nc1ccccc1)C2=O
InChI Key InChIKey=YHNXJITWZKVFPP-CVEARBPZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 395248
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 35nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair