BDBM395727 (+/−)-Cis-2-(4-((6S,9S)-9-(2-(difluoromethoxy)phenyl)-6-fluoro-6,7,8,9-tetrahydropyrido [4′,3′:4,5]imidazo[1,2-b]pyridazin-2-yl)phenyl)propan-2-ol::US10308652, Example 12::US10308652, Example 8

SMILES CC(C)(O)c1ccc(cc1)-c1ccc2nc3[C@@H](F)CN[C@H](c3n2n1)c1ccccc1OC(F)F

InChI Key InChIKey=QKYAEEBBOGFANY-UWJYYQICSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395727   

TargetTumor necrosis factor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM395727((+/−)-Cis-2-(4-((6S,9S)-9-(2-(difluoromethox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM395727((+/−)-Cis-2-(4-((6S,9S)-9-(2-(difluoromethox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent