BDBM395823 2-[5-cyclopropyl-4-(cyclopropylmethoxy)pyridin-2-yl]-3-oxa-1-azaspiro[4.5]dec-1-ene::US10308659, Example 22

SMILES C(Oc1cc(ncc1C1CC1)C1=NC2(CO1)CCCCC2)C1CC1

InChI Key InChIKey=OTHNBCCZCWKBPD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395823   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM395823(2-[5-cyclopropyl-4-(cyclopropylmethoxy)pyridin-2-y...)
Affinity DataEC50:  3.68E+3nMAssay Description:The affinity of the compounds of the invention for cannabinoid CB1 receptors was determined using recommended amounts of membrane preparations (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM395823(2-[5-cyclopropyl-4-(cyclopropylmethoxy)pyridin-2-y...)
Affinity DataEC50:  4.20nMAssay Description:The affinity of the compounds of the invention for cannabinoid CB1 receptors was determined using recommended amounts of membrane preparations (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent