BDBM397099 2-(5-methyl-2-{5-[(2-pyrrolidin-1- ylphenyl)carbonyl]hexahydropyrrolo [3,4-c]pyrrol-2(1H)-yl}-1,3- oxazol-4-yl)propan-2-ol::US9987255, 13

SMILES Cc1oc(nc1C(C)(C)O)N1CC2CN(CC2C1)C(=O)c1ccccc1N1CCCC1

InChI Key InChIKey=COHGSMSCNNUUOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397099   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397099(2-(5-methyl-2-{5-[(2-pyrrolidin-1- ylphenyl)carbon...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397099(2-(5-methyl-2-{5-[(2-pyrrolidin-1- ylphenyl)carbon...)
Affinity DataIC50:  49nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent