BDBM397123 N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-propyl-2-thiazolyl)-3-pyridinecarboxamide::US10456385, Example 16::US9987259, Example 16

SMILES CCCc1cnc(s1)-n1cc(ccc1=O)C(=O)NC1CN2CCC1CC2

InChI Key InChIKey=FESZKZXTFNCKJU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397123   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397123(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-propy...)
Affinity DataEC50:  300nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397123(N-(1-azabicyclo[2.2.2]octan-3-yl)-6-oxo-1-(5-propy...)
Affinity DataEC50:  300nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent