BDBM397140 (1-azabicyclo[2.2.2]octan-3-yl)-1-[5-methyl-1,3-thiadiazole-2-yl)-6-oxo-3-pyridinecarboxylate::US10456385, Example 45::US9987259, Example 45

SMILES Cc1cnc(s1)-n1cc(ccc1=O)C(=O)OC1CN2CCC1CC2

InChI Key InChIKey=WKOAHVHGLISSTG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397140   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397140((1-azabicyclo[2.2.2]octan-3-yl)-1-[5-methyl-1,3-th...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM397140((1-azabicyclo[2.2.2]octan-3-yl)-1-[5-methyl-1,3-th...)
Affinity DataEC50: >1.00E+3nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent