BDBM398168 4-Chloro-1-(tetrahydro-furan-3-yl)-1H-indole-3-carboxylic acid ((1S,4R)-1-bicyclo[2.2.1]hept-2-ylmethyl)-amide::US10323000, Compound 105::US10676433, Compound 105
SMILES Clc1cccc2n(cc(C(=O)NCC3C[C@@H]4CC[C@H]3C4)c12)C1CCOC1
InChI Key InChIKey=WDDAHMXWKXQTKQ-QVOMUQBLSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 398168
Affinity DataIC50: 55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair