BDBM398287 US10323016, Example 26
SMILES COc1ccc(cc1OC)N(C)c1cnc(SCc2c(F)cc(OCCCS([O-])(=O)=O)cc2F)n1-c1ccc(F)cc1
InChI Key InChIKey=AUGWFSKMKLCJIL-UHFFFAOYSA-M
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 398287
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Universite De Lille 2 Droit Et Sante
US Patent
Universite De Lille 2 Droit Et Sante
US Patent
Affinity DataEC50: 0.5nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante
US Patent
Universite De Lille 2 Droit Et Sante
US Patent
Affinity DataEC50: 40nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair