BDBM398804 1-((3S,4R)-4-(3,5- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3-yl)- 3-(3-(3-methoxypropyl)-4- methyl-1-phenyl-1H-pyrazol- 5-yl)urea::US10323022, Example 281

SMILES COCCCc1nn(c(NC(=O)N[C@@H]2CN(CCOC)C[C@H]2c2cc(F)cc(F)c2)c1C)-c1ccccc1

InChI Key InChIKey=HCVTXNBIOAJIRE-AZGAKELHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398804   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398804(1-((3S,4R)-4-(3,5- difluorophenyl)-1-(2- methoxyet...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent