BDBM398805 1-(3-(1,1-difluoro-2- hydroxyethyl)-4-methyl-1- phenyl-1H-pyrazol-5-yl)-3- ((3S,4R)-4-(3,4- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)urea::US10323022, Example 282
SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)C(F)(F)CO)[C@@H](C1)c1ccc(F)c(F)c1
InChI Key InChIKey=GYKCUFRYTFLENX-SIKLNZKXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 398805
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair