BDBM398806 1-(3-(1,1-difluoro-2- hydroxyethyl)-4-methyl-1- phenyl-1H-pyrazol-5-yl)-3- ((3S,4R)-4-(3,5- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)urea::US10323022, Example 283
SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)C(F)(F)CO)[C@@H](C1)c1cc(F)cc(F)c1
InChI Key InChIKey=WGUHNFSMFNHHNR-FCHUYYIVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 398806
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair