BDBM398817 1-(trans-4-(4-chloro-3- fluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3-yl)- 3-(1',4-dimethyl-1-phenyl- 1H,1'H-[3,4'-bipyrazol]-5- yl)urea::US10323022, Example 294

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2)-c2cnn(C)c2)C(C1)c1ccc(Cl)c(F)c1

InChI Key InChIKey=PCZLCVZNUUROJX-NRWPOFLRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398817   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398817(1-(trans-4-(4-chloro-3- fluorophenyl)-1-(2- methox...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent