BDBM398825 5-(3-(trans-4-(4-chloro-3- fluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)ureido)-N,4-dimethyl-1- phenyl-1H-pyrazole-3- carboxamide::US10323022, Example 302

SMILES CNC(=O)c1nn(c(NC(=O)N[C@@H]2CN(CCOC)CC2c2ccc(Cl)c(F)c2)c1C)-c1ccccc1

InChI Key InChIKey=MPBMUPIKKUVPPG-AVKWCDSFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398825   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398825(5-(3-(trans-4-(4-chloro-3- fluorophenyl)-1-(2- met...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent