BDBM398843 1-((3S,4R)-4-(4-fluorophenyl)- 1-(2-methoxyethyl)pyrrolidin- 3-yl)-3-(1-(2-fluorophenyl)- 1',4-dimethyl-1H,1'H-[3,4'- bipyrazol]-5-yl)urea::US10323022, Example 320

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccccc2F)-c2cnn(C)c2)[C@@H](C1)c1ccc(F)cc1

InChI Key InChIKey=QTVAWGVNVCLRHV-LADGPHEKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398843   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398843(1-((3S,4R)-4-(4-fluorophenyl)- 1-(2-methoxyethyl)p...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent