BDBM398845 1-(1-(3-chloro-4- fluorophenyl)-1',4-dimethyl- 1H,1'H-[3,4'-bipyrazol]-5-yl)- 3-((3S,4R)-4-(4- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)urea::US10323022, Example 322
SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccc(F)c(Cl)c2)-c2cnn(C)c2)[C@@H](C1)c1ccc(F)cc1
InChI Key InChIKey=FDSNBZFZSWDBOG-WIOPSUGQSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 398845
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair