BDBM398845 1-(1-(3-chloro-4- fluorophenyl)-1',4-dimethyl- 1H,1'H-[3,4'-bipyrazol]-5-yl)- 3-((3S,4R)-4-(4- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)urea::US10323022, Example 322

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(nn2-c2ccc(F)c(Cl)c2)-c2cnn(C)c2)[C@@H](C1)c1ccc(F)cc1

InChI Key InChIKey=FDSNBZFZSWDBOG-WIOPSUGQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398845   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398845(1-(1-(3-chloro-4- fluorophenyl)-1',4-dimethyl- 1H,...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent