BDBM401519 (S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(4-(2-(5- (dimethylamino)pyrazin-2-yl)-4- (trifluoromethyl)phenoxy)phenyl) pyrimidine-4-carboxamide::US10005768, Compound 134

SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(cc2-c2cnc(cn2)N(C)C)C(F)(F)F)cc1)C(N)=O)C(N)=O

InChI Key InChIKey=YSEULVXFOACYFD-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401519   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM401519((S)-6-((1-amino-1-oxopropan-2- yl)amino)-2-(4-(2-(...)
Affinity DataIC50:  393nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent