BDBM402655 5-{[(3R,4S)- or (3S,4R)-4- fluoropiperidin-3- yl]amino}-N-[1- methyl-3- (trifluoromethyl)-1H- pyrazol-4- yl]pyrazolo[1,5- a]pyrimidine-3- carboxamide::US10329294, Example 230

SMILES Cn1cc(NC(=O)c2cnn3ccc(N[C@@H]4CNCC[C@@H]4F)nc23)c(n1)C(F)(F)F

InChI Key InChIKey=SFTTZWACFKCMSY-WDEREUQCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402655   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402655(5-{[(3R,4S)- or (3S,4R)-4- fluoropiperidin-3- yl]a...)
Affinity DataIC50:  0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent