BDBM405075 1-(2-fluoro-4-{4-[2-(pyridin-2- yl)acetamido]-1H-1,2,3-triazol-1- yl}butyl)-N-{[2-fluoro-5- (trifluoromethoxy)phenyl]methyl}- 1H-1,2,3-triazole-4-carboxamide::US10344025, Example 419::US11370786, Example 419
SMILES FC(CCn1cc(NC(=O)Cc2ccccn2)nn1)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F
InChI Key InChIKey=LVYQAYLDGTUQFB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 405075
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair