BDBM405102 5-{3-fluoro-4-[4-({[4- (trifluoromethyl)pyridin-2- yl]methyl}carbamoyl)-1H-1,2,3- triazol-1-yl]butyl}-N-{[3- (trifluoromethoxy)phenyl]methyl}- 1,3,4-thiadiazole-2-carboxamide::US10344025, Example 446::US11370786, Example 446

SMILES FC(CCc1nnc(s1)C(=O)NCc1cccc(OC(F)(F)F)c1)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F

InChI Key InChIKey=PFGWKXBRXJECII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405102   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM405102(5-{3-fluoro-4-[4-({[4- (trifluoromethyl)pyridin-2-...)
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM405102(5-{3-fluoro-4-[4-({[4- (trifluoromethyl)pyridin-2-...)
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent