BDBM407374 4-(((1r,4R)-4-aminocyclo- hexyl)amino)-6-(3-cyano- pyrrolo[1,2-b]pyridazin-7- yl)-N-((R)-2-fluoro-3- hydroxy-3-methylbutyl) nicotinamide::US10336762, Compound 316
SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1N[C@H]1CC[C@H](N)CC1)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=BKCHWCDBZORKDL-SEPYTNNBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407374
Affinity DataIC50: <1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 136nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair