BDBM407908 (R)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-((5- (2,2-difluoroethoxy)pyridin- 3-yl)amino)-N-(2-fluoro- 3-hydroxy-3-methylbutyl) nicotinamide::US10336762, Compound 852

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1Nc1cncc(OCC(F)F)c1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=UVMGBPSGQMZDMF-HSZRJFAPSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 407908   

TargetTumor necrosis factor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM407908((R)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-((5...)
Affinity DataEC50:  3nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent