BDBM408517 6-(1-(2-(2-chloro-4-cyclopropylphenyl) propan-2-yl)-1H-1,2,3- triazol-4-yl)-2-methylpyrimdin- 4(3H)-one::US10358435, Example 34
SMILES Cc1nc(cc(=O)[nH]1)-c1cn(nn1)C(C)(C)c1ccc(cc1Cl)C1CC1
InChI Key InChIKey=URRZQVGZVLFRCC-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 408517
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 4.90nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair