BDBM408517 6-(1-(2-(2-chloro-4-cyclopropylphenyl) propan-2-yl)-1H-1,2,3- triazol-4-yl)-2-methylpyrimdin- 4(3H)-one::US10358435, Example 34

SMILES Cc1nc(cc(=O)[nH]1)-c1cn(nn1)C(C)(C)c1ccc(cc1Cl)C1CC1

InChI Key InChIKey=URRZQVGZVLFRCC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408517   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM408517(6-(1-(2-(2-chloro-4-cyclopropylphenyl) propan-2-yl...)
Affinity DataKi:  4.90nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent