BDBM408874 (E)-Methyl 3-(2-(N-(4-(6- (dimethylamino)pyridin-3- yl)benzyl) cyclohexanecarboxamido)pyridin-4- yl)acrylate::US10377717, Compound 5

SMILES COC(=O)\C=C\c1ccnc(c1)N(Cc1ccc(cc1)-c1ccc(nc1)N(C)C)C(=O)C1CCCCC1

InChI Key InChIKey=RBQIOMBINCMGML-LFIBNONCSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408874   

TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408874((E)-Methyl 3-(2-(N-(4-(6- (dimethylamino)pyridin-3...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent